876587-30-3Relevant academic research and scientific papers
A concise asymmetric route for the synthesis of a novel class of glucocorticoid mimetics containing a trifluoromethyl-substituted alcohol
Lee, Thomas W.,Proudfoot, John R.,Thomson, David S.
, p. 654 - 657 (2007/10/03)
An asymmetric route was developed for the synthesis of a class of novel glucocorticoid receptor ligand derivatives 1. The key step of this synthesis involves a diastereoselective addition of chiral sulfoxide anion to a trifluoromethyl ketone precursor. Th
