876587-31-4Relevant academic research and scientific papers
A concise asymmetric route for the synthesis of a novel class of glucocorticoid mimetics containing a trifluoromethyl-substituted alcohol
Lee, Thomas W.,Proudfoot, John R.,Thomson, David S.
, p. 654 - 657 (2007/10/03)
An asymmetric route was developed for the synthesis of a class of novel glucocorticoid receptor ligand derivatives 1. The key step of this synthesis involves a diastereoselective addition of chiral sulfoxide anion to a trifluoromethyl ketone precursor. Th
STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS
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Page/Page column 21, (2008/06/13)
A process for stereoselective synthesis of compounds of Formula (X) wherein: R1 is an aryl or heteroaryl group, each optionally independently substituted with one to three substituent groups, wherein each substituent group of R1 is i
