876590-06-6

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 3-[[(2-nitrophenyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R)-
• CAS NO: 876590-06-6
• Molecular Formula: C17H25N3O4
• Molecular Weight: 335.403
• Mol File: 876590-06-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 3-[[(2-nitrophenyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 3-[[(2-nitrophenyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R)-(876590-06-6)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 3-[[(2-nitrophenyl)amino]methyl]-, 1,1-dimethylethyl ester, (3R)-(876590-06-6)

Safety Data

• Hazardous Substances Data: 876590-06-6(Hazardous Substances Data)

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 140645-23-4 1,1-dimethylethyl (3R)-3-(aminomethyl)-1-piperidinecarboxylate 

Downstream Products

• 876590-07-7 1,1-dimethylethyl (3R)-3-{[(2-aminophenyl)amino]methyl}-1-piperidinecarboxylate 

Relevant articles and documents

Novel N-substituted benzimidazole CXCR4 antagonists as potential anti-HIV agents

The lead optimization of a series of N-substituted benzimidazole CXCR4 antagonists is described. Side chain modifications and stereochemical optimization led to substantial improvements in potency and protein shift to afford compounds with low nanomolar a

CHEMICAL COMPOUNDS

The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.