140645-23-4

Basic information

• Product Name: (R)-N-Boc-3-aminomethylpiperidine
• Synonyms: (R)-3-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(R)-3-AMINOMETHYL-1-N-BOC-PIPERIDINE;(R)-1-N-BOC-3-(AMINOMETHYL)PIPERIDINE;(R)-1-N-BOC-PIPERIDINE-3-METHYLAMINE;(R)-1-BOC-3-(AMINOMETHYL)PIPERIDINE;(R)-N-BOC-3-AMINOMETHYLPIPERIDINE;(R)-TERT-BUTYL 3-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE;1,1-dimethyl (3R)-3-(aminomethyl)-1-piperidinecarboxylate
• CAS NO: 140645-23-4
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.3
• Product Categories: Building Blocks;C11;Chemical Synthesis;Heterocyclic Building Blocks;Piperidines
• Mol File: 140645-23-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 299.4 °C at 760 mmHg
• Flash Point: >110°C
• Appearance: Clear colorless to pale yellow/Liquid
• Density: 0.997g/mLat 25℃
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: n20/D 1.473
• Storage Temp.: 2-8°C
• PKA: 10.12±0.29(Predicted)
• CAS DataBase Reference: (R)-N-Boc-3-aminomethylpiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-Boc-3-aminomethylpiperidine(140645-23-4)
• EPA Substance Registry System: (R)-N-Boc-3-aminomethylpiperidine(140645-23-4)

Safety Data

• Hazard Codes: Xi,Xn,N
• Statements: 22-50-36/37/38
• Safety Statements: 26-61
• RIDADR: UN 3082 9 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 140645-23-4(Hazardous Substances Data)

Usage

General Description

(R)-N-Boc-3-aminomethylpiperidine is a chemical compound that consists of a piperidine ring with a Boc (tert-butyloxycarbonyl) protecting group attached to the nitrogen atom and an aminoethyl group attached to the 3-position of the piperidine ring. It is commonly used as an intermediate in the synthesis of various pharmaceutical compounds and organic molecules. The Boc protecting group helps to prevent unwanted reactions at the nitrogen atom, and the 3-aminomethylpiperidine moiety provides a reactive amine group for further functionalization. (R)-N-Boc-3-aminomethylpiperidine is utilized in the field of medicinal chemistry and organic synthesis to create novel drug candidates and other biologically active compounds.

InChI:InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-5-9(7-12)8-13/h9H,4-8,12H2,1-3H3

Upstream product

• 4606-65-9 (S)-(hydroxymethyl)piperidine 
• 191092-08-7 tert-butyl (3S)-3-[[(4-methylbenzenesulfonyl)oxy]methyl]piperidine-1-carboxylate 
• 191599-51-6 ethyl (S)-1-[(tert-butoxy)carbonyl]piperidine-3-carboxylate 
• 37675-18-6 (S)-(+)-nipecotic acid ethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 364356-44-5 (S)-<<(methylsulfonyl)oxy>methyl>piperidine-1-carboxylic acid tert-butyl ester 
• 140695-84-7 tert-butyl (3S)-3-(hydroxymethyl)piperidine-1-carboxylate 
• 140645-22-3 (3S)-3-azidomethyl-1-(tert-butoxycarbonyl)-piperidine 

Downstream Products

• 879396-20-0 (S)-1-Piperidin-3-ylmethyl-carbamic acid benzyl ester 
• 875270-50-1 (R)-tert-butyl 3-((5-bromo-2-(2,4-difluorobenzamido)benzamido)methyl)piperidine-1-carboxylate 
• 875269-98-0 tert-butyl (3R)-3-({[5-bromo-2-(isobutyrylamino)benzoyl]amino}-methyl)piperidine-1-carboxylate 
• 876590-06-6 1,1-dimethylethyl (3R)-3-{[(2-nitrophenyl)amino]methyl}-1-piperidinecarboxylate 
• 879275-35-1 (R)-<<(benzyloxycarbonyl)amino>methyl>piperidine-1-carboxylic acid tert-butyl ester 
• 1190706-83-2 (S)-6-(2-chlorophenyl)-N-(3,4-difluorobenzyl)-7-(piperidin-3-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine trifluoroacetate 
• 1190707-38-0 (R)-tert-butyl 3-((6-(2-chlorophenyl)-2-(3,4-difluorobenzylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)piperidine-1-carboxylate 
• 1190707-36-8 (R)-tert-butyl 3-((2-chloro-5-((2-chlorophenyl)ethynyl)pyrimidin-4-ylamino)methyl)piperidine-1-carboxylate 
• 1190707-37-9 (R)-tert-butyl 3-((2-chloro-6-(2-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl)piperidine-1-carboxylate 

Relevant articles and documents

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