876687-03-5

Upstream product

• 139-85-5 3,4-dihydroxybenzaldehyde 
• 29668-44-8 2,3-dihydro-benzo[1,4]dioxin-6-carbaldehyde 
• 2124-31-4 4'-dimethylaminoacetophenone 

Downstream Products

• 1350927-84-2 5-(2,3-dihydro-1,4-benzodioxane-6-yl)-3-(4-(N,N-dimethylamino)phenyl)-4,5-dihydro-1H-pyrazole 

Relevant academic research and scientific papers

Synthesis and antihepatotoxic activity of 5-(2,3-dihydro-1,4-benzodioxane- 6-yl)-3-substituted-phenyl-4,5-dihydro-1H-pyrazole derivatives

In continuance of our search for newer antihepatotoxic agents some novel pyrazoline derivatives containing 1,4-dioxane ring system were synthesized starting from 3-(2,3-dihydro-1,4-benzodioxane-6-yl)-1-substituted-phenylprop-2- en-1-one. Some of the synthesized compounds were evaluated for antihepatotoxic activity against CCl4-induced hepatotoxicity in rats. Among them some compounds have shown significant antihepatotoxic activity comparable to standard drug silymarin.