876708-01-9

Usage

Uses

Used in Medicinal Chemistry:
2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs targeting specific biological pathways.
Used in Drug Development:
In the field of drug development, 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) serves as a potential candidate for the creation of novel therapeutic agents. Its azide group and pyrimidine ring may contribute to the compound's ability to modulate biological processes and target specific enzymes or receptors.
Used in Nucleic Acid Research:
2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) is utilized in the study of nucleic acids and nucleoside analogs. Its structure allows researchers to investigate its interactions with enzymes and biological pathways involved in nucleic acid metabolism and DNA replication, potentially leading to advancements in understanding and treating related diseases.
Further research is necessary to fully explore the potential uses and applications of 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)(9CI) in these and other fields.

Upstream product

• 876707-99-2 2,2'-anhydro-1-(4'-azido-β-D-arabinofuranosyl)uracil 
• 139442-01-6 1-(4'-azido-β-D-ribofuranosyl)uracil 

Downstream Products

• 876708-03-1 4'-azidoarabinocytidine 
• 1365255-42-0 C₃₀H₂₃N₅O₉ 

Relevant academic research and scientific papers

Azido nucleosides and nucleotide analogs

Disclosed herein are 4′-azido-substituted nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of 4′-azido-substituted nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a 4′-azido-substituted nucleoside, a nucleotide and/or an analog thereof. Examples of viral infections include a respiratory syncytial viral (RSV) and influenza infection.

AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS

Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of amelioratin

The design, synthesis, and antiviral activity of 4′-azidocytidine analogues against hepatitis C virus replication: The discovery of 4′-azidoarabinocytidine

4′-Azidocytidine 3 (R1479) has been previously discovered as a potent and selective inhibitor of HCV replication targeting the RNA-dependent RNA polymerase of hepatitis C virus, NS5B. Here we describe the synthesis and biological evaluation of several der

Anti-viral nucleosides

4-Amino-1-((2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one (I:R1=R2=R3=R4=H) and prodrugs thereof are hepatitis C(HCV) polymerase inhibitors. Also disclosed are comp