876708-01-9

Basic information

• Product Name: 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)- (9CI)
• Synonyms: 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)- (9CI);Nucleoside-Analog-2;CS-M1996
• CAS NO: 876708-01-9
• Molecular Formula: C9H11N5O6
• Molecular Weight: 285.21354
• Mol File: 876708-01-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)- (9CI)(876708-01-9)
• EPA Substance Registry System: 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)- (9CI)(876708-01-9)

Safety Data

• Hazardous Substances Data: 876708-01-9(Hazardous Substances Data)

Usage

General Description

2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)- (9CI) is a chemical compound that contains a pyrimidine ring and an azide functional group attached to a β-D-arabinofuranosyl sugar molecule. The azide group is a common functional group in organic chemistry and is used in a variety of chemical reactions. The compound may have potential applications in the field of medicinal chemistry and drug development, as well as in the study of nucleic acids and nucleoside analogs. Additionally, the presence of the pyrimidine ring suggests potential interactions with enzymes and biological pathways involved in nucleic acid metabolism and DNA replication. Further research is needed to fully understand the potential uses and applications of this chemical compound.

Upstream product

• 139442-01-6 1-(4'-azido-β-D-ribofuranosyl)uracil 
• 876707-99-2 2,2'-anhydro-1-(4'-azido-β-D-arabinofuranosyl)uracil 

Downstream Products

• 876708-03-1 4'-azidoarabinocytidine 
• 1365255-42-0 C₃₀H₂₃N₅O₉ 

Relevant articles and documents

Azido nucleosides and nucleotide analogs

Disclosed herein are 4′-azido-substituted nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of 4′-azido-substituted nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a 4′-azido-substituted nucleoside, a nucleotide and/or an analog thereof. Examples of viral infections include a respiratory syncytial viral (RSV) and influenza infection.

The design, synthesis, and antiviral activity of 4′-azidocytidine analogues against hepatitis C virus replication: The discovery of 4′-azidoarabinocytidine

4′-Azidocytidine 3 (R1479) has been previously discovered as a potent and selective inhibitor of HCV replication targeting the RNA-dependent RNA polymerase of hepatitis C virus, NS5B. Here we describe the synthesis and biological evaluation of several der