876716-91-5Relevant academic research and scientific papers
Single-site chemical modification at C10 of the baccatin III core of paclitaxel and Taxol C reduces P-glycoprotein interactions in bovine brain microvessel endothelial cells
Spletstoser, Jared T.,Turunen, Brandon J.,Desino, Kelly,Rice, Antonie,Datta, Apurba,Dutta, Dinah,Huff, Jacquelyn K.,Himes, Richard H.,Audus, Kenneth L.,Seelig, Anna,Georg, Gunda I.
, p. 495 - 498 (2006)
A single-site modification of paclitaxel analogs at the C10 position on the baccatin III core that reduces interaction with P-glycoprotein in bovine brain microvessel endothelial cells is described. Modification and derivatization of the C10 position were
