87674-18-8

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Bromonicotinamide is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique structure allows for the creation of a wide range of medicinal compounds.
Used in Agrochemical Production:
In the agrochemical industry, 2-Bromonicotinamide is utilized as a building block in the synthesis of different agrochemicals, playing a crucial role in the development of pesticides and other agricultural chemicals to enhance crop protection and yield.
Used in Organic Synthesis:
As a versatile building block, 2-Bromonicotinamide is employed in organic synthesis for the creation of a variety of organic compounds, expanding the scope of chemical research and development.
Used in Biological Research:
2-Bromonicotinamide is used as a subject of study in biological research for its potential as an anti-inflammatory and anti-cancer agent. Its exploration in these areas could lead to advancements in medical treatments and therapies.
Used in the Development of Therapeutic Agents:
Due to its potential biological activities, 2-Bromonicotinamide is used in the development of therapeutic agents, particularly for conditions such as inflammation and cancer, offering new possibilities for treatment and patient care.

InChI:InChI=1/C6H5BrN2O/c7-5-4(6(8)10)2-1-3-9-5/h1-3H,(H2,8,10)

Upstream product

• 35905-85-2 2-bromonicotinic acid 
• 3430-17-9 2-bromo-3-picoline 

Downstream Products

• 39856-58-1 3-amino-2-bromopyridine 
• 1446393-89-0 sodium (2-bromonicotinoyl)(3-methoxybenzoyl)amide 
• 1446357-54-5 2-(3-methoxyphenyl)-4H-pyrido[3,2-e][1,3]oxazin-4-one 
• 1446393-87-8 C₁₃H₈BrN₂O₂^(1-)*Na⁽¹⁺⁾ 
• 1446357-52-3 2-phenyl-4H-pyrido[3,2-e][1,3]oxazin-4-one 
• 1446393-90-3 sodium (2-bromonicotinoyl)(2-fluorobenzoyl)amide 
• 1446357-55-6 2-(2-fluorophenyl)-4H-pyrido[3,2-e][1,3]oxazin-4-one 
• 16081-87-1 2-phenylpyrido<2,3-d>pyrimidin-4(3H)-one 
• 1446357-53-4 2-(m-tolyl)-4H-pyrido[3,2-e][1,3]oxazin-4-one 
• 1446393-88-9 sodium (2-bromonicotinoyl)(3-methylbenzoyl)amide 

Relevant academic research and scientific papers

Phosphazene Superbase-Mediated Regio- and Stereoselective Iodoaminocyclization of 2-(1-Alkynyl)benzamides for the Synthesis of Isoindolin-1-ones

Phosphazene superbase P4-t-Bu mediated iodoaminocyclization of 2-(1-alkynyl)benzamides is reported. The reaction works under ambient conditions and instantaneously results in the synthesis of isoindolin-1-ones in 65-97% yields, in a regio- and stereoselective manner. The exclusive formation of products with Z-geometry (across the exo C?C bond) has been confirmed through X-ray crystallography. The methodology also provides an easy access to aristolactams, an important class of natural products. This has been successfully demonstrated by synthesizing two aristolactam derivatives (including Cepharanone B).