87674-18-8 Usage
General Description
2-Bromonicotinamide is a chemical compound that belongs to the class of organic compounds known as pyridine carboxamides. It is a white crystalline solid with a molecular formula C6H5BrN2O. 2-BROMONICOTINAMIDE is used in the synthesis of various pharmaceuticals and agrochemicals. It is also employed as a building block in organic synthesis. Additionally, 2-Bromonicotinamide has been studied for its potential biological activities and therapeutic applications, including as an anti-inflammatory and anti-cancer agent. Overall, 2-Bromonicotinamide is a versatile and important chemical compound with various industrial and research applications.
Check Digit Verification of cas no
The CAS Registry Mumber 87674-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,6,7 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 87674-18:
(7*8)+(6*7)+(5*6)+(4*7)+(3*4)+(2*1)+(1*8)=178
178 % 10 = 8
So 87674-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H5BrN2O/c7-5-4(6(8)10)2-1-3-9-5/h1-3H,(H2,8,10)
87674-18-8Relevant articles and documents
Phosphazene Superbase-Mediated Regio- and Stereoselective Iodoaminocyclization of 2-(1-Alkynyl)benzamides for the Synthesis of Isoindolin-1-ones
Mehta, Saurabh,Brahmchari, Dhirendra
supporting information, p. 5492 - 5503 (2019/05/10)
Phosphazene superbase P4-t-Bu mediated iodoaminocyclization of 2-(1-alkynyl)benzamides is reported. The reaction works under ambient conditions and instantaneously results in the synthesis of isoindolin-1-ones in 65-97% yields, in a regio- and stereoselective manner. The exclusive formation of products with Z-geometry (across the exo C?C bond) has been confirmed through X-ray crystallography. The methodology also provides an easy access to aristolactams, an important class of natural products. This has been successfully demonstrated by synthesizing two aristolactam derivatives (including Cepharanone B).