87679-18-3

Usage

Uses

Used in Organic Synthesis:
(1s,3R,5S)-3,5-dimethylcyclohexane-1-carboxylic acid is utilized as a key intermediate in various organic synthesis reactions. Its unique structure and reactivity make it a versatile building block for creating a range of chemical products.
Used in Pharmaceutical Synthesis:
As a potential building block, (1s,3R,5S)-3,5-dimethylcyclohexane-1-carboxylic acid is used in the synthesis of pharmaceuticals and other biologically active compounds. Its specific stereochemistry and functional groups contribute to the development of new drugs and therapeutic agents.
Used in Chemical Research:
(1s,3R,5S)-3,5-dimethylcyclohexane-1-carboxylic acid serves as a valuable compound for research in organic chemistry. Its properties and reactivity are studied to understand and develop new synthetic methods, reactions, and applications in the chemical industry.

Upstream product

• 31673-46-8 3,5-dimethylcyclohexa-2,5-diene-1-carboxylic acid 
• 638-04-0 cis-1,3-dimethylcyclohexane 
• 201230-82-2 carbon monoxide 
• 499-06-9 3,5-dimethylbenzoic acid 

Downstream Products

• 68480-16-0 cis-3,cis-5-dimethyl-r-1-(hydroxymethyl)cyclohexane 

Relevant academic research and scientific papers

AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17

The present invention relates to a compound according to formula I (I) and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.

Experimental Demonstration of a Sizeable Nonclassical CH···G Hydrogen Bond in Cyclohexane Derivatives: Stabilization of an Axial Cyano Group

Base-catalyzed equilibration of anancomeric cyanocyclohexanes demonstrates that replacement of cis-3,5-dimethyl holding groups with electron-withdrawing CF3 groups dramatically increases the proportion of the axial cyano isomer present at equilibrium. The CF3 groups exert an effect on the conformational energy of the cyano group worth about 0.6 kcal/mol. A nonclassical hydrogen bond between the axial CN group and the syn-axial hydrogens is a major contributor to the axial stability of the group.

Enantio- and Regioselective Ir-Catalyzed Hydrogenation of Di- and Trisubstituted Cycloalkenes

A number of cyclic olefins were prepared and evaluated for the asymmetric hydrogenation reaction using novel N,P-ligated iridium imidazole-based catalysts (Crabtree type). The diversity of these cyclic olefins spanned those having little functionality to

Pd-Catalyzed Regio- and Stereo-selective Carboxylation of Cycloalkanes with CO

The reactions of cycloalkanes with CO via the C-H bond activation by Pd(OAc)2 catalyst have been found to proceed regio- and stereo-selectively to give corresponding carboxylic acids.The reactivity of C-H bonds of cycloalkanes decreases in the order: tert- > sec- > prim-carbon, and the stereochemistry of the substitutents on the main products is all equatorial.