876893-22-0Relevant academic research and scientific papers
Efficient microwave access to polysubstituted amidines from imidoylbenzotriazoles
Katritzky, Alan R.,Cai, Chunming,Singh, Sandeep K.
, p. 3375 - 3380 (2007/10/03)
Microwave reactions of primary and secondary amines with imidoylbenzotriazoles 6a-w gave diversely substituted amidines 7a-Aa in 76-94% yields. Convenient preparations of a variety of amides 5a-Ab (87-96%) and imidoylbenzotriazoles 6a-w (56-95%) have also been developed using microwave irradiation under mild conditions and short reaction times. These results demonstrate further the advantages of microwave synthesis and introduce a new application of imidoylbenzotriazoles in the preparation of polysubstituted amidines.
