876911-15-8 Usage
Uses
Used in Organic Synthesis:
8-BROMO-2,2-DIMETHYL-4H-BENZO[1,3]DIOXINE is used as a starting material in organic synthesis for its unique structural features, which can be further modified to produce a variety of chemical derivatives with different properties and applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 8-BROMO-2,2-DIMETHYL-4H-BENZO[1,3]DIOXINE is utilized as a key intermediate in the development of new drugs. Its chemical properties make it a valuable component in the synthesis of potential therapeutic agents.
Used in Drug Development:
8-BROMO-2,2-DIMETHYL-4H-BENZO[1,3]DIOXINE is studied for its potential use in the development of new medical treatments. Its unique structure and reactivity may contribute to the creation of novel pharmaceutical compounds with improved efficacy and selectivity for specific therapeutic targets.
Used in Chemical Research:
In the field of chemical research, 8-BROMO-2,2-DIMETHYL-4H-BENZO[1,3]DIOXINE serves as a subject of study to understand its reactivity, stability, and potential interactions with other molecules. This knowledge can be applied to design new chemical processes and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 876911-15-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,6,9,1 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 876911-15:
(8*8)+(7*7)+(6*6)+(5*9)+(4*1)+(3*1)+(2*1)+(1*5)=208
208 % 10 = 8
So 876911-15-8 is a valid CAS Registry Number.
876911-15-8Relevant academic research and scientific papers
Second-generation cycloSal-d4TMP pronucleotides bearing esterase-cleavable sites - The "trapping" concept
Meier, Chris,Ducho, Christian,Jessen, Henning,Vukadinovic-Tenter, Dalibor,Balzarini, Jan
, p. 197 - 206 (2007/10/03)
An extension of the cycloSal-pronucleotide approach is presented. Attachment of an enzyme-cleavable ester/acylal group to the cycloSal-d4TMP triesters should allow these compounds to be trapped intracellularly after cleavage. The ester/acylal groups were introduced in the 3- or 5-position of the cycloSal ring system, and surprising differences were observed in hydrolysis studies in CEM cell extracts with respect to the ester/acylal moiety. While acetyl and levulinyl esters were readily cleaved, alkyl esters of cycloSal-d4TMP acids proved to be resistant to enzymatic cleavage. In contrast, AM-, POM- and POC-acylals were rapidly cleaved in the extracts, leading to cycloSal-d4TMP acids. The antiviral activity of the compounds against HIV is also presented. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
Novel cycloSal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase
Ducho,Jessel,Gisch,Balzarini,Meier
, p. 519 - 522 (2008/02/02)
Two novel cycloSal-d4T monophosphates (d4TMPs) with increased stem demand have been synthesized via a new synthetic route. While 3-cyclohexyl-cycloSal d4TMP did not show a significantly reduced inhibitory potency toward human butyrylcholinesterase, the opposite was the case for the second novel pronucleotide, bis-(cycloSal-d4TMP). Copyright Taylor & Francis, Inc.
