8-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine

Base Information

Chemical Name:8-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine
CAS No.:876911-15-8
Molecular Formula:C10H11BrO2
Molecular Weight:243.1
Hs Code.:2932999099
DSSTox Substance ID:DTXSID60467519
Wikidata:Q82294491
Mol file:876911-15-8.mol

Synonyms:876911-15-8;8-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine;8-BROMO-2,2-DIMETHYL-4H-BENZO[1,3]DIOXINE;4H-1,3-Benzodioxin, 8-bromo-2,2-dimethyl-;8-BROMO-2,2-DIMETHYL-4H-1,3-BENZODIOXINE;8-Bromo-2,2-dimethyl-2,4-dihydro-1,3-benzodioxine;SCHEMBL12191290;DTXSID60467519;BKB91115;SB39286;EN300-383224;8-Bromo-2,2-dimethyl-2H,4H-1,3-benzodioxine

Suppliers and Price of 8-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
8-Bromo-2,2-dimethyl-4H-benzo[1,3]dioxine 96%
500mg
$ 349.00

J&W Pharmlab
8-Bromo-2,2-dimethyl-4H-benzo[1,3]dioxine 96%
5g
$ 1998.00

J&W Pharmlab
8-Bromo-2,2-dimethyl-4H-benzo[1,3]dioxine 96%
1g
$ 598.00

Chemenu
8-Bromo-2,2-dimethyl-4H-benzo[1,3]dioxine 95%
1g
$ 574.00

American Custom Chemicals Corporation
8-BROMO-2,2-DIMETHYL-4H-BENZO(1,3)DIOXINE 96.00%
5MG
$ 503.57

Alichem
8-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine
1g
$ 544.50

Total 8 raw suppliers

Chemical Property of 8-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine

Chemical Property:

PSA：18.46000
LogP:3.09420
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:241.99424
Heavy Atom Count:13
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

8-Bromo-2,2-dimethyl-4H-benzo[1,3]dioxine 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OCC2=C(O1)C(=CC=C2)Br)C

Technology Process of 8-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine

There total 2 articles about 8-Bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 28165-46-0
3-bromo-2-hydroxybenzyl alcohol

: 77-76-9
2,2-dimethoxy-propane

: 876911-15-8
3-bromosalicyl alcohol isopropylidene acetal

Guidance literature:: With toluene-4-sulfonic acid; sodium sulfate; In acetone; at 40 ℃; for 72h;
DOI:10.1002/ejoc.200500490

Reference yield:

: 95-56-7
2-hydroxybromobenzene

: 876911-15-8
3-bromosalicyl alcohol isopropylidene acetal

Guidance literature:: Multi-step reaction with 2 steps

1.1: PhB(OH)2; C₂H₅COOH / toluene / 18 h / Heating

1.2: 53 percent / H₂O₂ / H₂O; tetrahydrofuran / 0.75 h / 0 °C

2.1: 99 percent / p-TsOH; Na₂SO₄ / acetone / 72 h / 40 °C

With toluene-4-sulfonic acid; propionic acid; sodium sulfate; phenylboronic acid; In acetone; toluene;
DOI:10.1081/NCN-200061791

Reference yield:

: 876911-15-8
3-bromosalicyl alcohol isopropylidene acetal

: 931-50-0
cyclohexylmagnesium bromide

: 73779-18-7
3-cyclohexylsalicyl alcohol

Guidance literature:: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 16h;
DOI:10.1081/NCN-200061791