87692-43-1

Basic information

• Product Name: (1S,3R,4R,5R)-4-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentane-1,3-diol
• Synonyms: (1S,3R,4R,5R)-4-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentane-1,3-diol
• CAS NO: 87692-43-1
• Molecular Weight: 488.783
• Mol File: 87692-43-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,3R,4R,5R)-4-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentane-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3R,4R,5R)-4-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentane-1,3-diol(87692-43-1)
• EPA Substance Registry System: (1S,3R,4R,5R)-4-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentane-1,3-diol(87692-43-1)

Safety Data

• Hazardous Substances Data: 87692-43-1(Hazardous Substances Data)

Upstream product

• 87692-39-5 15α-O-(t-butyldimethylsilyl)-5,6-dihydro-5,6-dihydroxy-PGF_2α methyl ester 
• 87692-37-3 (Z)-7-{(1S,2R,3R,5S)-2-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-4-oxo-6-oxa-bicyclo[3.1.0]hex-3-yl}-hept-5-enoic acid methyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 87692-38-4 15α-O-(t-butyldimethylsilyl)-PGE₂ methyl ester 
• 65147-38-8 15α-O-(t-butyldimethylsilyl)-PGF_2α methyl ester 
• 53122-04-6 15α-O-t-butyldimethylsilyl-PGA₂ methyl ester 
• 31753-19-2 (5Z,13E)-15-hydroxy-9-oxoprosta 5,10,13 trien-1-oic acid 
• 13345-50-1 prostaglandin A₂ 
• 3462-97-3 (4-methoxybenzyl)triphenylphosphonium bromide 

Downstream Products

• 87692-44-2 (1S,3R,4R,5R)-4-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentane-1,3-diol 

Relevant articles and documents

Synthesis of Aromatic Modified Prostaglandins from PGA2

A general synthetic scheme, starting from PGA2 (obtained from the marine coral Plexaura homomalla), of prostaglandins modified in the upper chain is detailed.Key aldehyde intermediates have been secured from 11-deoxy-PGF2α and PGF2α by an efficient regioselective hydroxylation procedure followed by cleavage of the 5,6-double bond.Witting reaction with these aldehydes provided the novel prostaglandins (5)-(8), belonging to the E and F families, and containing an aromatic ring in the upper chain.