876926-04-4

Basic information

• Product Name: 1H-Imidazole, 2-bromo-1-[2-(4-chlorophenyl)ethyl]-
• CAS NO: 876926-04-4
• Molecular Formula: C11H10BrClN2
• Molecular Weight: 285.571
• Mol File: 876926-04-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 2-bromo-1-[2-(4-chlorophenyl)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 2-bromo-1-[2-(4-chlorophenyl)ethyl]-(876926-04-4)
• EPA Substance Registry System: 1H-Imidazole, 2-bromo-1-[2-(4-chlorophenyl)ethyl]-(876926-04-4)

Safety Data

• Hazardous Substances Data: 876926-04-4(Hazardous Substances Data)

Upstream product

• 16681-56-4 2-bromo-1H-imidazole 
• 6529-53-9 1-(2-bromoethyl)-4-chlorobenzene 

Downstream Products

• 876926-11-3 9-chloro-5,6-dihydroimidazo[2,1-a]isoquinoline 
• 56643-90-4 1-[2-(4-chlorophenyl)ethyl]-1H-imidazole 

Relevant articles and documents

Photochemical intramolecular aromatic substitutions of the imidazol-2-yl radical are superior to those mediated by Bu3SnH

Six-membered photochemical cyclisations of 2-iodo-N-(2-arylethyl)imidazoles proceeded regioselectively in higher yields than the equivalent tin hydride-mediated reactions. The decrease in yield of cyclisation products, 5,6-dihydroimidazo[2,1-a]isoquinolines containing strongly deactivating substituents on the aryl ring confirmed the electrophilic nature of the σ-imidazol-2-yl radicals. The seven-membered cyclisation was only successful under photochemical conditions, as radical reduction occurred with tin hydride. Nitration of 5,6-dihydroimidazo[2,1-a]isoquinoline with nitric/sulfuric acid occurred at the 2- and 8-positions. The Royal Society of Chemistry 2006.