87693-22-9

Basic information

• Product Name: 2-methyl-6-nitro-N-1H-tetrazol-5-ylbenzamide
• Synonyms: 2-methyl-6-nitro-N-1H-tetrazol-5-ylbenzamide
• CAS NO: 87693-22-9
• Molecular Weight: 248.201
• Mol File: 87693-22-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-methyl-6-nitro-N-1H-tetrazol-5-ylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-6-nitro-N-1H-tetrazol-5-ylbenzamide(87693-22-9)
• EPA Substance Registry System: 2-methyl-6-nitro-N-1H-tetrazol-5-ylbenzamide(87693-22-9)

Safety Data

• Hazardous Substances Data: 87693-22-9(Hazardous Substances Data)

Upstream product

• 13506-76-8 2-methyl-6-nitrobenzoic acid 
• 66232-57-3 2-methyl-6-nitrobenzoyl chloride 
• 15454-54-3 5-amino-1H-tetrazole monohydrate 
• 4418-61-5 5-aminotetrazole 

Downstream Products

• 87693-15-0 2-amino-6-methyl-N-1H-tetrazol-5-ylbenzamide 

Relevant articles and documents

3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinone Sodium Salt (MDL 427): A New Antiallergic Agent

Syntheses for 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinone sodium salt monohydrate (9; MDL 427) and the related formamido compound, 2-(formylamino)-N-1H-tetrazol-5-ylbenzamide (10), are described.Both compounds are active in the rat passive cutaneous anaphylaxis and passive peritoneal anaphylaxis tests.A 94:6 equilibrium mixture of 9 and ionized 10, respectively, forms in aqueous buffer systems at a pH-dependent rate.In addition, analogues of 3-(1H-tetrazol-5-yl)-4(3H)-quinazolinone (8) bearing substituents on the benzene ring, substituents at the 2-position, and heteroaryl groups at the 3-position other than tetrazole were prepared.These analogue sets demonstrated that an accessible electrophilic center and an acidic functionality were requirements for good antiallergic activity.