87698-85-9Relevant academic research and scientific papers
HETEROCYCLIC DERIVATIVES AS RORGAMMA MODULATORS
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Page/Page column 71-72, (2016/07/27)
The present invention provides novel compounds of formula (I) that are modulators of RORgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of RORgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, fibrotic diseases, or cholestatic diseases.
"tert-Amino Effect" in Heterocyclic Synthesis. Formation of N-Heterocycles by Ring-Closure Reactions of Substituted 2-Vinyl-N,N-dialkylanilines
Verboom, Willem,Reinhoudt, David N.,Visser, Richard,Harkema, Sybolt
, p. 269 - 276 (2007/10/02)
2-Vinyl-N,N-dialkylanilines react thermally in polar solvents and/or in the presence of Lewis acids via or hydrogen transfer followed by C-C bond formation to give heterotricyclic compounds.The reaction depends on the type of N,N-dialkylamino
