877032-07-0

Basic information

• Product Name: Cyclohexanone, 2-[(R)-hydroxy(3-nitrophenyl)methyl]-, (2S)-
• CAS NO: 877032-07-0
• Molecular Formula: C13H15NO4
• Molecular Weight: 249.266
• Mol File: 877032-07-0.mol
• Article Data: 201

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2-[(R)-hydroxy(3-nitrophenyl)methyl]-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2-[(R)-hydroxy(3-nitrophenyl)methyl]-, (2S)-(877032-07-0)
• EPA Substance Registry System: Cyclohexanone, 2-[(R)-hydroxy(3-nitrophenyl)methyl]-, (2S)-(877032-07-0)

Safety Data

• Hazardous Substances Data: 877032-07-0(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 99-61-6 3-nitro-benzaldehyde 
• 619-25-0 3-Nitrobenzyl alcohol 
• 108-93-0 cyclohexanol 
• 3395-79-7 m-nitrobenzaldehyde dimethylacetal 
• 555-16-8 4-nitrobenzaldehdye 
• 552-89-6 2-nitro-benzaldehyde 

Relevant articles and documents

A chemo-enzymatic oxidation/aldol sequential process directly converts arylbenzyl alcohols and cyclohexanol into chiral β-hydroxy carbonyls

The development of a combination enzyme and organocatalyst for aqueous sequential organic transformation has great significance, in that it is not only environmentally friendly but also overcomes only a single methodological drawback, either in the chemical or biological process. Herein, through the utilization of the bulky steric hindrance of chiral proline derivatives, an integrated laccase and proline as a chemo-enzymatic co-catalyst system is developed. It enables an efficient oxidation/aldol enantioselective sequential reaction to be accomplished, overcoming the mutual deactivation issue. As we present in this study, this one-pot organic transformation, an initial laccase-mediated oxidation of arylbenzyl alcohols and cyclohexanol to form aldehydes and cyclohexanone, followed by a subsequent proline derivative-catalyzed aldol condensation of the in situ generated intermediates, provides various 1,2-diastereoisomeric chiral β-hydroxy ketones with acceptable yields and high enantio-/diastereoselectivities.

Direct Asymmetric Aldol Reaction in Continuous Flow Using Gel-Bound Organocatalysts

Continuous flow catalysis using a microfluidic reactor with gel-bound proline organocatalysts is an attractive approach in organic synthesis due to interesting advantages such as the permanent production of catalyst-free products and the easy product isol

Pro-phe derivatives as organocatalysts in asymmetric aldol reaction

The aldol reaction which is the most important one among the C-C bond forming reactions, is widely used by synthetic organic chemists to obtain β-hydroxycarbonyl compounds which are important starting components for biologically active compounds in optica