87708-17-6

Basic information

• Product Name: N,N-diethyl-2-oxo-1,3-oxazolidine-3-sulfonamide
• CAS NO: 87708-17-6
• Molecular Formula: C₇H₁₄N₂O₄S
• Molecular Weight: 222.2621
• Mol File: 87708-17-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 308.1°C at 760 mmHg
• Flash Point: 140.1°C
• Density: 1.36g/cm³
• Vapor Pressure: 0.000697mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: N,N-diethyl-2-oxo-1,3-oxazolidine-3-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-2-oxo-1,3-oxazolidine-3-sulfonamide(87708-17-6)
• EPA Substance Registry System: N,N-diethyl-2-oxo-1,3-oxazolidine-3-sulfonamide(87708-17-6)

Safety Data

• Hazardous Substances Data: 87708-17-6(Hazardous Substances Data)

Upstream product

• 109-89-7 diethylamine 
• 87708-19-8 2-chloroethyl chlorosulfonylcarbamate 
• 87708-07-4 N-(chloro-2 ethoxycarbonyl) N',N'-(diethyl) sulfamide 

Relevant articles and documents

Mild and safer preparative method for nonsymmetrical sulfamides via N-sulfamoyloxazolidinone derivatives: Electronic effects affect the transsulfamoylation reactivity

Sulfamides (R1R2N-SO2-NR3R 4) are traditionally prepared by using strong electrophilic and hazardous reagents such as N-sulfamoyl chloride, sulfonyl chloride, phosphorus oxychloride, or phosphorus pentachloride. We report here a safer and more convenient synthetic methodology for large-scale preparation of sulfamides using the N-substituted oxazolidin-2-one derivatives 5 as synthetic equivalent of the corrosive and hazardous N-sulfamoyl chloride. The scope of the use of N-sulfamoyloxazolidinones to prepare nonsymmetrical sulfamides is explored.

SELECTIVE SYNTHESIS OF SULFONYLUREAS AND CARBOXYSULFAMIDES. A NOVEL ROUTE TO OXAZOLIDINES.

Starting with chlorosulfonylisocyanate (CSI) two new series of 2-haloethyl carboxysulfamides 5 and 2-haloethyl oxosulfonylureas 6 have been prepared.The haloethyl carboxylate 5 underwent a novel cyclisation in the presence of Et3N to furnish quantitative