877081-06-6

Basic information

• Product Name: Azetidine, 3-(1-methylethyl)-1-[(4-methylphenyl)sulfonyl]-2-phenyl-, (2S,3S)-
• CAS NO: 877081-06-6
• Molecular Formula: C19H23NO2S
• Molecular Weight: 329.463
• Mol File: 877081-06-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Azetidine, 3-(1-methylethyl)-1-[(4-methylphenyl)sulfonyl]-2-phenyl-, (2S,3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Azetidine, 3-(1-methylethyl)-1-[(4-methylphenyl)sulfonyl]-2-phenyl-, (2S,3S)-(877081-06-6)
• EPA Substance Registry System: Azetidine, 3-(1-methylethyl)-1-[(4-methylphenyl)sulfonyl]-2-phenyl-, (2S,3S)-(877081-06-6)

Safety Data

• Hazardous Substances Data: 877081-06-6(Hazardous Substances Data)

Upstream product

• 72203-95-3 ((S)-2-Methoxymethyl-pyrrolidin-1-yl)-[3-methyl-but-(E)-ylidene]-amine 
• 877080-96-1 (E,2R)-2-{[2-(trimethylsilyl)ethoxy]methyl}-N-[(S)-2-(methoxymethyl)pyrrolidin-1-yl]-3-methylbutan-1-imine 
• 877081-01-1 (1S,2R)-2-{[2-(trimethylsilyl)ethoxy]methyl}-3-methyl-1-phenyl-N-tosylbutan-1-amine 

Relevant articles and documents

Asymmetric synthesis of substituted azetidine type α- and β-amino acids

A versatile asymmetric synthesis of 3-substituted azetidine-2-carboxylic acids and 2-substituted azetidine-3-carboxylic acids via 1,3-amino alcohols with excellent stereoselectivities (de ≥ 96%, ee ≥ 96%) is reported. The high asymmetric inductions were achieved employing the SAMP/RAMP-hydrazone methodology. A phenyl moiety was used as a synthetic equivalent of the carboxylic acid function. In addition, the amino acids prepared were tested as organocatalysts in an asymmetric aldol reaction. Georg Thieme Verlag Stuttgart.