877131-92-5

Usage

Uses

Used in Pharmaceutical Industry:
4-bromo-2-trifluoromethylphenylacetonitrile is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of a wide range of therapeutic agents, contributing to the development of new medications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-bromo-2-trifluoromethylphenylacetonitrile is utilized as a key component in the preparation of agrochemicals. Its role in this industry is crucial for the synthesis of effective and targeted pest control agents.
Used in Materials Science:
4-bromo-2-trifluoromethylphenylacetonitrile is employed as a reagent in organic synthesis, particularly for the preparation of photochromic materials. Its ability to change color upon exposure to light makes it a valuable component in the development of smart materials and devices.
Used in Organic Synthesis:
As a versatile intermediate, 4-bromo-2-trifluoromethylphenylacetonitrile is used in the preparation of various chiral molecules. Its presence in organic synthesis is significant for creating enantiomerically pure compounds, which are essential in many chemical and pharmaceutical applications.

Upstream product

• 335013-18-8 4-bromo-1-(bromomethyl)-2-(trifluoromethyl)benzene 
• 151-50-8 potassium cyanide 
• 86845-27-4 4-bromo-1-methyl-2-(trifluoromethyl) benzene 
• 773837-37-9 sodium cyanide 
• 1214350-42-1 4-bromo-1-(chloromethyl)-2-(trifluoromethyl)benzene 
• 7677-24-9 trimethylsilyl cyanide 
• 320-31-0 4-bromo-2-(trifluoromethyl)benzoic acid 

Downstream Products

• 877131-96-9 1-(4-bromo-2-trifluoromethyl-phenyl)-cyclopropanecarbonitrile 

Relevant academic research and scientific papers

ANTIMICROBIAL COMPOUNDS AND METHODS

The invention is directed to compounds that are active as antibacterial agents. The invention compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes and intermediates for making the compounds.

ANTIMICROBIAL COMPOUNDS AND METHODS

The invention is directed to compounds that are active as antibacterial agents. The invention compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes and intermediates for making the compounds.

PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to pyrimidine derivatives of formula (I) wherein (R1)n, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (II) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.

RENIN INHIBITORS

The present invention relates to biphenyl compounds of formula (I). These compounds are renin inhibitors of a non- peptidic nature and of low molecular weight. The invention further relates to a pharmaceutical composition containing said compounds, as wel

INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME

The present invention provides compounds of formula (4), and their pharmaceutically acceptable salts and solvates, which are useful as inhibitors of the Hepatitis C virus (HCV) polymerase enzyme and are also useful for the treatment of HCV infections in HCV-infected mammals. The present invention also provides pharmaceutical compositions comprising compounds of formula (4), their pharmaceutically acceptable salts and solvates. Furthermore, the present invention provides intermediate compounds and methods useful in the preparation of compounds of formula (4).

BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS

Disclosed is an excellent LXR modulator. Specifically disclosed is a compound represented by the general formula (I) below or the like. (I) [In the formula, R1 represents a -COR9 (wherein R9 represents an alkyl, optionally substituted alkoxy or optionally substituted amino); R2 represents an H, OH, alkoxy, optionally substituted amino or the like; R3 represents an H, optionally substituted alkyl, cycloalkyl, optionally substituted alkoxy, optionally substituted amino, halogeno or the like; R4 and R5 respectively represent an H, optionally substituted alkyl, halogeno or the like; R6 and R7 respectively represent an H or alkyl; R8 represents a -X2R10 [wherein R10 represents a -COR11 (wherein R11 represents an OH, optionally substituted alkoxy, optionally substituted amino or the like), -SO2R12 (wherein R12 represents an optionally substituted alkyl, optionally substituted amino or the like), tetrazole-5-yl or the like; and X2 represents a single bond, optionally substituted alkylene or the like]; X1 represents an -NH-, -O-, -S- or the like; Y1 represents an optionally substituted phenyl or optionally substituted 5-membered or 6-membered aromatic heterocyclyl; and Y2 represents an optionally substituted aryl, substituted heterocyclyl or the like.]