877154-23-9Relevant academic research and scientific papers
A novel synthesis and molluscicidal activity of some functionally substituted pyridine, pyrido-[3,2-c]pyridazine, and pyrido[3,2-c]pyridazino- [2′,3′-a]quinazoline derivatives
Abdelrazek, Fathy M.,Fathy, Alaa El-Din M.
, p. 329 - 334 (2007/10/03)
Ethyl benzoylacetate reacts with the malononitrile dimer to afford 4-amino-5-benzoyl-2-dicyano-methyl-6-hydroxypyridine, which undergoes the coupling reaction with aromatic diazonium salts to afford azo derivatives. These azo derivatives could be cyclized into pyrido[3,2-c]pyridazine and pyrido[3,2-c]pyridazino[2′,3′-a]quinazoline derivatives upon reflux in ethanolic NaOH, presumably via their hydrazo tautomers. The molluscicidal activity of these compounds was evaluated.
