877160-80-0Relevant academic research and scientific papers
Tetrahydroquinoline glucocorticoid receptor agonists: Discovery of a 3-hydroxyl for improving receptor selectivity
Roach, Steven L.,Higuchi, Robert I.,Hudson, Andrew R.,Adams, Mark E.,Syka, Peter M.,Mais, Dale E.,Miner, Jeffrey N.,Marschke, Keith B.,Zhi, Lin
scheme or table, p. 168 - 171 (2011/02/27)
We have previously disclosed a series of glucocorticoid receptor (GR) ligands derived from 6-indole-1,2,3,4-tetrahydroquinolines through structure-activity relationship (SAR) of the pendent C6-indole ring. In parallel with this effort, we now report SAR o
INTRACELLULAR RECEPTOR MODULATOR COMPOUNDS AND METHODS
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Page/Page column 134, (2010/10/20)
This invention relates to compounds of Formula I, II or III with the definitions of R1-R10 according to claim 1 that bind to intracellular receptors and/or modulate activity of intracellular receptors, and to methods for making and using such compounds.
