87718-66-9

Upstream product

• 5292-53-5 diethyl benzalmalonate 
• 72293-08-4 trans-3-ethoxycarbonyl-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-one 
• 137-07-5 2-amino-benzenethiol 
• 72293-09-5 trans-2,3-dihydro-3-hydroxymethyl-2-phenyl-1,5-benzothiazepin-4(5H)-one 
• 72293-16-4 trans-3-chloromethyl-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-one 
• 72293-07-3 ethyl 3-(2-aminophenylthio)-2-ethoxycarbonyl-3-phenylpropionate 

Downstream Products

• 87707-95-7 3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzthiazepin-4(5H)-one 
• 117553-81-8 3-[4-(2-Hydroxy-ethyl)-piperazin-1-ylmethyl]-2-phenyl-5H-benzo[b][1,4]thiazepin-4-one 

Relevant academic research and scientific papers

Synthesis of a new potent anti-ulcer and gastric secretory inhibiting agent, (-)-cis-2,3-dihidro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiaze pin-4(5H)-one hydrochloride (BTM-1086), and related compounds

(-)-cis-2,3-Dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiazepin-4(5H)-one hydrochloride (BTM-1086) and its analogues, which possessed potent anti-ulcer and gastric secretory inhibiting activities, were synthesized and the structure of these compounds were established on the basis of spectral and chemical evidences.