87727-93-3

Basic information

• Product Name: (1S,2R,3R)-3-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-2-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentanol
• Synonyms: (1S,2R,3R)-3-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-2-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentanol
• CAS NO: 87727-93-3
• Molecular Weight: 472.784
• Mol File: 87727-93-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2R,3R)-3-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-2-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R,3R)-3-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-2-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentanol(87727-93-3)
• EPA Substance Registry System: (1S,2R,3R)-3-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-2-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentanol(87727-93-3)

Safety Data

• Hazardous Substances Data: 87727-93-3(Hazardous Substances Data)

Upstream product

• 87692-32-8 15α-O-(t-butyldimethylsilyl)-11-deoxy-5,6-dihydro-5,6-dihydroxy-PGF_2α methyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 87692-31-7 15α-O-(t-butyldimethylsilyl)-11-deoxy-PGF_2α methyl ester 
• 53122-04-6 15α-O-t-butyldimethylsilyl-PGA₂ methyl ester 
• 31753-19-2 (5Z,13E)-15-hydroxy-9-oxoprosta 5,10,13 trien-1-oic acid 
• 13345-50-1 prostaglandin A₂ 
• 3462-97-3 (4-methoxybenzyl)triphenylphosphonium bromide 
• 87700-38-7 {(1R,2R,5S)-2-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-hydroxy-cyclopentyl}-acetaldehyde 

Downstream Products

• 87727-96-6 (2R,3R)-3-((E)-(S)-3-Hydroxy-oct-1-enyl)-2-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentanone 
• 87727-95-5 (2R,3R)-3-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-2-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentanone 
• 87727-94-4 (1S,2R,3R)-3-((E)-(S)-3-Hydroxy-oct-1-enyl)-2-[(Z)-3-(4-methoxy-phenyl)-allyl]-cyclopentanol 

Relevant articles and documents

Synthesis of Aromatic Modified Prostaglandins from PGA2

A general synthetic scheme, starting from PGA2 (obtained from the marine coral Plexaura homomalla), of prostaglandins modified in the upper chain is detailed.Key aldehyde intermediates have been secured from 11-deoxy-PGF2α and PGF2α by an efficient regioselective hydroxylation procedure followed by cleavage of the 5,6-double bond.Witting reaction with these aldehydes provided the novel prostaglandins (5)-(8), belonging to the E and F families, and containing an aromatic ring in the upper chain.