877287-55-3

Upstream product

• 494799-19-8 methyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate 
• 87199-14-2 2-(hydroxymethyl)phenylboronic acid 
• 877283-07-3 11-cyclohexyl-5-hydroxy-5H-pyrido[2',3':3,4]pyrrolo[1,2-a]indole-8-carboxylic acid methyl ester 

Downstream Products

• 902148-65-6 methyl 2-[2-({[tert-butyl(dimethyl)silyl]oxy}methyl)phenyl]-3-cyclohexyl-1H-indole-6-carboxylate 
• 956580-44-2 methyl 3-cyclohexyl-2-(2-{[(triisopropylsilyl)oxy]methyl}phenyl)-1H-indole-6-carboxylate 
• 877287-63-3 C₂₃H₂₄ClNO₂ 

Relevant academic research and scientific papers

PENTACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention relates to pentacyclic indole derivatives of formula (I): wherein A, Ar, R1, R2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.

Inhibitors of HCV replication

Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.