877387-18-3

Basic information

• Product Name: C₁₈H₁₈N₂O₅
• CAS NO: 877387-18-3
• Molecular Weight: 342.351
• Mol File: 877387-18-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₈N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₈N₂O₅(877387-18-3)
• EPA Substance Registry System: C₁₈H₁₈N₂O₅(877387-18-3)

Safety Data

• Hazardous Substances Data: 877387-18-3(Hazardous Substances Data)

Upstream product

• 1016-19-9 3,4,5-trimethoxyphenylisocyanate 
• 19745-72-3 ω-amino-4-hydroxyacetophenone hydrochloride 

Relevant articles and documents

Synthesis and biological evaluation of imidazol-2-one derivatives as potential antitumor agents

A new series of aryl substituted imidazol-2-one derivatives structurally related to combretastatin A-4 (CA-4) were synthesized and evaluated for their cytotoxic activities in vitro against various human cancer cell lines including MDR cell line. The cytotoxic effects of compounds 7b and 7i proved to be similar to or greater than that of docetaxel. The highly active compound 7b also exhibited excellent inhibitory activity on tumor growth in vivo.