87752-94-1

Basic information

• Product Name: 2-phenyl-3,5,6,7,8,9-hexahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one
• Synonyms: 2-Phenyl-3,5,6,7,8,9-hexahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one; 4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one, 3,5,6,7,8,9-hexahydro-2-phenyl-
• CAS NO: 87752-94-1
• Molecular Formula: C₁₇H₁₆N₂OS
• Molecular Weight: 296.3867
• Mol File: 87752-94-1.mol

Chemical Properties

• Boiling Point: 423.6°C at 760 mmHg
• Flash Point: 210°C
• Density: 1.38g/cm³
• Vapor Pressure: 8.97E-08mmHg at 25°C
• Refractive Index: 1.733
• CAS DataBase Reference: 2-phenyl-3,5,6,7,8,9-hexahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-3,5,6,7,8,9-hexahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one(87752-94-1)
• EPA Substance Registry System: 2-phenyl-3,5,6,7,8,9-hexahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one(87752-94-1)

Safety Data

• Hazardous Substances Data: 87752-94-1(Hazardous Substances Data)

Upstream product

• 40106-13-6 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester 
• 100-47-0 benzonitrile 
• 502-42-1 cycloheptanone 
• 40106-12-5 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 87752-99-6 4-Chloro-2-phenyl-6,7,8,9-tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulene 
• 943827-41-6 2-phenyl-4-hydrazino-5,6,7,8,9-pentahydrocyclohepta[b]thieno[2,3-d]pyrimidine 

Relevant articles and documents

Exploiting drug-resistant enzymes as tools to identify thienopyrimidinone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H

The thienopyrimidinone 5,6-dimethyl-2-(4-nitrophenyl)thieno[2,3-d] pyrimidin-4(3H)-one (DNTP) occupies the interface between the p66 ribonuclease H (RNase H) domain and p51 thumb of human immunodeficiency virus reverse transcriptase (HIV RT), thereby indu

Synthesis and antibacterial activity of some novel triazolothienopyrimidines

A novel series of some novel 5-substituted-1,2,4-triazolo[4,3-c]8,9,10- trihydrocyclopenta/8,9,10,11,12-pentahydrocyclohepta[ b]thieno[3,2-e]pyrimidin- 3-thiones has been synthesized. The intermediates 4-chloro-2-substituted-5,6,7- trihydrocyclopenta/5,6,

Thieno[2.3-d]-4-pyrimidones: Synthesis, structure and pharmacological properties

The cyclization of 2-amino-3-carbethoxy or -carboxamido thophenes yields substituted or unsubstituted 4-pyrimidones. Their structure and their 'lactam-lactam' tautomerism have been investigated by i.r. spectroscopy. The eighteen compounds synthesized were tested for a few pharmacological activities. They have no anti-edema activity except for two. Ten of them have shown an analgesic activity equal or superior to that of acetyl salicylic acid.