87758-64-3Relevant academic research and scientific papers
Towards the Total Synthesis of the Norsesterterpene Diacarnoxide C
Schneider, Marc-André,Seifert, Karlheinz
supporting information, p. 6739 - 6746 (2017/12/07)
The synthesis of the norsesterterpene diacarnoxide C was achieved. The endoperoxide moiety could be prepared in nine and the norsesquiterpene moiety in five steps starting from (E)-3-methyl-6-oxohex-2-en-1-yl acetate and dihydro-β-ionone. The peroxide ald
Asymmetric aldol reactions on a soluble polymeric support
Reggelin,Brenig,Zur
, p. 531 - 533 (2007/10/03)
(Formula presented) The combinatorial synthesis of small, nonpeptidic compounds is of increasing interest in current medicinal chemistry. To meet this demand, efficient entries, preferentially on polymeric supports, to pharmacologically interesting classes of compounds such as polyketides are necessary. Therefore, we have developed a synthetic protocol allowing for the asymmetric synthesis of diketides on the soluble support MeOPEG-5000. The strategy employed mainly allows for repeated aldolizations, thus providing access to functionalized polyketides of varying degree of oligomerization.
