149836-92-0

Upstream product

• 87758-64-3 C₁₇H₃₂BNO₃ 
• 81445-44-5 (S)-2-(benzyloxy)propanal 

Downstream Products

• 149885-12-1 (2S,3R)-2-((S)-1-Benzyloxy-ethyl)-3-tert-butoxycarbonylamino-butyric acid 
• 149885-10-9 [(1R,2S)-2-((S)-1-Benzyloxy-ethyl)-1-methyl-but-3-ynyl]-carbamic acid tert-butyl ester 
• 175656-30-1 (2S,3S)-2-((R)-1-Amino-ethyl)-3-benzyloxy-butyric acid 
• 145072-02-2 2-[(2R,3R)-3-((S)-1-Benzyloxy-ethyl)-2-methyl-pent-4-ynoylamino]-4,5,6,7-tetrahydro-2H-isoindole-1-carboxylic acid methyl ester 
• 145072-06-6 2-[(3R,4R)-3-((S)-1-Benzyloxy-ethyl)-4-methyl-2-methylene-5-oxo-pyrrolidin-1-yl]-4,5,6,7-tetrahydro-2H-isoindole-1-carboxylic acid methyl ester 
• 145071-98-3 (2R,3R)-3-((S)-1-Benzyloxy-ethyl)-2-methyl-pent-4-ynoic acid 

Relevant academic research and scientific papers

Studies on the Synthesis of Phytochrome and Related Tetrapyrroles. Dihydropyrromethenones by Photochemical Rearrangement of N-Pyrrolo Enamides

Dihydropyrromethenone 67b, a potential precursor for the synthesis of phytochrome 1, has been prepared in enantiomerically pure form beginning with N-aminopyrrole 64 and the acetylenic acid 62b. The key step involved a 3,5-sigmatropic rearrangement of N-pyrrolo enamide 66b.

Formal total syntheses of the β-lactam antibiotics thienamycin and PS-5

Chiral nonracemic acetylenic acids of general structure 11, prepared using the Schreiber modification of the Nicholas reaction, have been converted to β-amino acid derivatives of type 12 by a two-step sequence involving Curtius rearrangement followed by o