877615-09-3Relevant articles and documents
Design, synthesis, and evaluation of 2-alkoxydihydrocinnamates as PPAR agonists
Lu, Ying,Guo, Zongru,Guo, Yanshen,Feng, Jun,Chu, Fengming
, p. 915 - 919 (2007/10/03)
A series of 2-alkoxydihydrocinnamates were synthesized as PPARγ and PPARα dual agonists. In vitro studies in cell model showed that these compounds were efficacious. Compound 1g was found to be a potent PPARα/γ dual agonist and will be further evaluated for the treatment of type II diabetes.