87767-72-4Relevant articles and documents
A new class of nitrosoureas. VIII. Synthesis and antitumor activity of 3-substituted 1-(2-chloroethyl)-3-(trans-2-hydroxy-cyclohexyl)-1-nitrosoureas
Morikawa,Tsujihara,Takeda,Arai
, p. 1646 - 1651 (1983)
A series of six 3-substituted 1-(2-chloroethyl)-3-(trans-2-hydroxycyclohexyl)-1-nitrosoureas (IVa-f) was prepared and tested for antitumor activities. Heating of cyclohexene oxide with various alkylamines followed by reaction with 2-chloroethyl isocyanate