A new class of nitrosoureas. VIII. Synthesis and antitumor activity of 3-substituted 1-(2-chloroethyl)-3-(trans-2-hydroxy-cyclohexyl)-1-nitrosoureas

DOI: 10.1248/cpb.31.1646

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1646 - 1651 (1983)

Update date:2022-08-02

Topics:

Authors:

Morikawa

Tsujihara

Takeda Takeda

Arai Arai

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.31.1646

A series of six 3-substituted 1-(2-chloroethyl)-3-(trans-2-hydroxycyclohexyl)-1-nitrosoureas (IVa-f) was prepared and tested for antitumor activities. Heating of cyclohexene oxide with various alkylamines followed by reaction with 2-chloroethyl isocyanate

Full text of DOI:10.1248/cpb.31.1646

NII-Electronic Library Service

Products guided by the article

Product name:(1R,2R)-2-(2-Methoxy-ethylamino)-cyclohexanol

Cas No:87767-72-4

R&D Labs maybe for 87767-72-4

chengdu firsterchem Pharmaceutical Co., Ltd.

Contact:028-66825849

Address:chengdu
ZiBO KuoDing Trade company Ltd

website:http://www.sdzbkd.com

Contact:86-13361591822

Address:GongQingTuan road
WEIFANG RICHEM INTERNATIONAL LTD

Contact:86-536-2222176

Address:weifang,shandong
Fusilin chemical science & technology co., ltd.

Contact:532-80698166/86057573, +86-400-669-7885

Address:School of Material Science & Engineering, Shandong Uinversity of Science & Technology, Huangdao Zone, Qindao, Shandong
Chinapeptides Co,. Ltd

Contact:+86-021-50792271

Address:Building 24A, 300 Chuantu Road, Chuansha, Pudong new area, Shanghai, China, 201202

Relevant to this article

Ruthenium-catalyzed reaction of α,β-unsaturated imines with carbon monoxide and alkenes leading to β,γ-unsaturated γ-butyrolactams: Involvement of direct carbonylation at olefinic C-H bonds as a key step

Doi:10.1021/jo026001m
(2002)
Synthesis, characterization and reactivity of polypyridyl ruthenium(II) carbonyl complexes with phosphine derivatives: Ruthenium-carbon bond labilization based on steric and electronic effects

Doi:10.1016/j.ica.2005.04.040
(2006)
Synthesis, bioactivities, and X-ray structure analysis of 2-cyano-5-methylpyrazolo[1,5-a]pyrimidine

Doi:10.1007/s10870-005-3475-y
(2005)
An efficient conversion of alcohols to alkyl bromides using pyridinium based ionic liquids: A green alternative to appel reaction

Doi:10.14233/ajchem.2018.21086
(2018)
Structural Studies on Mixed Iron-Gold Clusters with Bidentate Tertiary Phosphine Ligands

Doi:10.1039/c39830000843
(1983)
A new synthetic approach to pyrrolo[3,4-a]indolizines

Doi:10.1055/s-2005-918510
(2006)

Article Doi