877671-66-4Relevant academic research and scientific papers
LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES
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Page/Page column 24; 47-48, (2008/06/13)
Reactive fluorescent dyes compositions and methods of using same are disclosed. Squaraine nucleus, Nile red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed dyes are disclosed having thiol-reactive groups. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed that exhibit a fluorescence emission of at least about 575 nm. Biosensors are disclosed having a binding protein and a squaraine nucleus, Nile Red nucleus, benzodiaxazole nucleus, coumarin nucleus or aza coumarin nucleus.
Coumarin derivatives, process for their preparation, their use and thiazolyl acetic acid derivatives as intermediates
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, (2008/06/13)
Coumarin deviatives of the formula STR1 in which R1 denotes cyano, R2 represents phenyl or thiazolyl bonded in the 2-, 4-, or 5-position, R3 denotes hydrogen, C1 -C4 -alkyl or C1 -C4 -alkoxycarbonyl-C1 -C4 -alkyl and R4 represents hydrogen, C1 -C4 -alkyl or phenylsulphonyl, where C1 -C4 -alkyl can be substituted by hydroxyl, amino, carboxyl or C1 -C4 -alkoxy-carbonyl and phenyl can be monosubstituted or disubstituted by chlorine, bromine or C1 -C4 -alkyl, where furthermore R3 and R4, together with the N atom which they substitute, can denote a morpholine ring, a piperazine ring or a triazole ring which can carry one or two substituents from the group comprising methyl, ethyl and phenyl, and where furthermore one of the radicals R2, R3 and R4 denotes or carries a primary or secondary amino group, the hydroxyl group, the carboxyl group or the C1 -C4 -alkoxy-carbonyl group or can be converted into such a group by hydrolysis or hydrogenation, are suitable for dyeing biologically active compounds.
