877678-80-3Relevant academic research and scientific papers
A convenient synthesis of highly substituted 3-N,N-dialkylamino-1,2,4- triazoles
Batchelor, David V.,Beal, David M.,Brown, T. Bruce,Ellis, David,Gordon, David W.,Johnson, Patrick S.,Mason, Helen J.,Ralph, Michael J.,Underwood, Toby J.,Wheeler, Simon
experimental part, p. 2421 - 2424 (2009/04/08)
The title compounds are prepared from S-methylisothioureas and acyl hydrazides in moderate to good yields. The reaction is characterized by relatively mild conditions and very broad functional group tolerance. Georg Thieme Verlag Stuttgart.
TRIAZOLOBENZODIAZEPINES AND THEIR USE AS VASOPRESSIN ANTAGONISTS
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Page/Page column 36, (2010/10/20)
Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein R represents H, C1-6 alkyl, SO2R1, SO2NR1R2, or COR1; R1 and R2 independently represent C1-6alkyl; and Ring A represents a phenyl ring or a pyridinyl ring; may be useful in the treatment of anxiety, cardiovascular disease (including angina, atherosclerosis, hypertension, heart failure, edema, hypernatremia), dysmenorrhoea (primary and secondary), endometriosis, emesis (including motion sickness), intrauterine growth retardation, inflammation (including rheumatoid arthritis), mittlesmerchz, preclampsia, premature ejaculation, premature (preterm) labor and Raynaud's disease.
