87771-41-3

Basic information

• Product Name: 1-[3-(2-hydroxypropan-2-yl)phenyl]ethanone
• Synonyms: 1-[3-(2-hydroxypropan-2-yl)phenyl]ethanone;Ethanone, 1-[3-(1-hydroxy-1-methylethyl)phenyl]-
• CAS NO: 87771-41-3
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.22766
• Mol File: 87771-41-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 276.2±15.0 °C(Predicted)
• Appearance: /
• Density: 1.056±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 14.20±0.29(Predicted)
• CAS DataBase Reference: 1-[3-(2-hydroxypropan-2-yl)phenyl]ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-(2-hydroxypropan-2-yl)phenyl]ethanone(87771-41-3)
• EPA Substance Registry System: 1-[3-(2-hydroxypropan-2-yl)phenyl]ethanone(87771-41-3)

Safety Data

• Hazardous Substances Data: 87771-41-3(Hazardous Substances Data)

Usage

Uses

1-(3-(2-Hydroxypropan-2-yl)phenyl)ethanone is a useful reagent for the synthesis of bioactive small molecules with multiple biological applications.

Upstream product

• 13387-60-5 3-(2-hydroxy-2-propyl)-1-(2-hydroperoxy-2-propyl)benzene 
• 1397293-24-1 3-acetyl-α,α-dimethylbenzylamine 
• 1397293-17-2 3-acetyl-α,α-dimethylbenzyl isocyanate 
• 2094-99-7 1-(1-isocyanato-1-methylethyl)-3-(1-methylethenyl)benzene 
• 1397293-26-3 C₁₁H₁₅NO₄S 
• 108-10-1 4-methyl-2-pentanone 
• 99-62-7 1,3-diisopropylbenzene 
• 80937-33-3 oxygen 

Downstream Products

• 87771-42-4 1-(3-(prop-1-en-2-yl)phenyl)ethanone 

Relevant articles and documents

COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS

Disclosed are compounds and pharmaceutically acceptable salts thereof, which are useful as inhibitors of IMPDH. In certain embodiments, a compound selectively inhibits a parasitic IMPDH versus a host IMPDH. Also disclosed are pharmaceutical compositions comprising one or more compounds of the invention. Related methods of treating various parasitic and bacterial infections in mammals are disclosed. Moreover, the compounds may be used alone or in combination with other therapeutic or prophylactic agents, such as anti-virals, anti-inflammatory agents, antimicrobials and immunosuppressants.

Process for the production of a dihydroxybenzene and dicarbinol from diisopropylbenzene

Improved methods for the simultaneous production of dihydroxybenzene and dicarbinol from diisopropylbenzene are provided. These methods provide for continuous and simultaneous production of diisopropylbenzene dihydroperoxide (DHP) and diisopropylbenzene hydroxyhydroperoxide (HHP) using Karr Column extractors operated in series. A very high purity DHP-containing solution, the precursor to the dihydroxybenzene, can be produced according to the reported methods. A safe and efficient method for producing dicarbinol from HHP is also disclosed.