877776-33-5Relevant academic research and scientific papers
Remote asymmetric trifluoromethylation induced by chiral sulfinyl group: Synthesis of enantiomerically pure 1-(2-naphthyl)-2,2,2-trifluoroethanol
Sugimoto, Hideki,Nakamura, Shuichi,Shibata, Yoshihiro,Shibata, Norio,Toru, Takeshi
, p. 1337 - 1340 (2006)
The reaction of 1-[(2,4,6-triisopropylphenyl)sulfinyl]-2-naphthaldehyde with (trifluoromethyl)trimethylsilane using tetramethylammonium fluoride gave trifluoromethylated compounds in high yield with high diastereoselectivity. Desilylation and subsequent r
