87782-49-8 Usage
Uses
Used in Anticancer Applications:
1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil is used as an anticancer agent for its ability to inhibit the growth of various cancer cell lines. Its mechanism of action involves disrupting the essential DNA and RNA processes, thereby hindering cell proliferation and survival. FdU has shown promising results in preclinical studies and is being explored for its potential use in cancer therapy.
Used in Antiviral Applications:
In the field of antiviral treatment, 1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil is used as a therapeutic agent against herpes simplex virus infections. Its antiviral properties make it a candidate for further investigation and potential development as a treatment option for such viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 87782-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,7,8 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87782-49:
(7*8)+(6*7)+(5*7)+(4*8)+(3*2)+(2*4)+(1*9)=188
188 % 10 = 8
So 87782-49-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H13FN2O5/c1-2-5-3-14(11(18)13-9(5)17)10-7(12)8(16)6(4-15)19-10/h2-3,6-8,10,15-16H,1,4H2,(H,13,17,18)/t6-,7+,8-,10-/m1/s1
87782-49-8Relevant academic research and scientific papers
Watanabe,Su,Reichman,Greenberg,Lopez,Fox
, p. 91 - 94 (1984)
Synthesis of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils containing a vinyl (4a), 2-halovinyl (4b-d), or ethyl substituent at C-5 was achieved. These nucleosides were found to be about a log order less active than 2'-fluoro-5-iodo-ara-C (FIAC) aga