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1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil, also known as FdU, is a synthetic nucleoside analogue derived from the nucleoside uracil. It features a fluorinated deoxyribose sugar molecule connected to a fluoroarabinofuranosyl group and a vinyl group. FdU is specifically engineered to interfere with the replication and transcription processes of DNA and RNA, which are vital for cell growth and survival. 1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil has demonstrated potential antitumor effects and antiviral properties, particularly against herpes simplex virus infections.

87782-49-8

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87782-49-8 Usage

Uses

Used in Anticancer Applications:
1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil is used as an anticancer agent for its ability to inhibit the growth of various cancer cell lines. Its mechanism of action involves disrupting the essential DNA and RNA processes, thereby hindering cell proliferation and survival. FdU has shown promising results in preclinical studies and is being explored for its potential use in cancer therapy.
Used in Antiviral Applications:
In the field of antiviral treatment, 1-(2-deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil is used as a therapeutic agent against herpes simplex virus infections. Its antiviral properties make it a candidate for further investigation and potential development as a treatment option for such viral infections.

Check Digit Verification of cas no

The CAS Registry Mumber 87782-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,7,8 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87782-49:
(7*8)+(6*7)+(5*7)+(4*8)+(3*2)+(2*4)+(1*9)=188
188 % 10 = 8
So 87782-49-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H13FN2O5/c1-2-5-3-14(11(18)13-9(5)17)10-7(12)8(16)6(4-15)19-10/h2-3,6-8,10,15-16H,1,4H2,(H,13,17,18)/t6-,7+,8-,10-/m1/s1

87782-49-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-Deoxy-(2-fluoroarabinofuranosyl))-5-vinyluracil

1.2 Other means of identification

Product number -
Other names 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-vinyluracil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:87782-49-8 SDS

87782-49-8Downstream Products

87782-49-8Relevant academic research and scientific papers

Nucleosides. 129. Synthesis of antiviral nucleosides: 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils.

Watanabe,Su,Reichman,Greenberg,Lopez,Fox

, p. 91 - 94 (1984)

Synthesis of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils containing a vinyl (4a), 2-halovinyl (4b-d), or ethyl substituent at C-5 was achieved. These nucleosides were found to be about a log order less active than 2'-fluoro-5-iodo-ara-C (FIAC) aga

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