87783-59-3Relevant academic research and scientific papers
Irreversible inactivation of papain and cathepsin B by epoxidic substrate analogues
Giordano, C.,Gallina, C.,Consalvi, V.,Scandurra, R.
, p. 479 - 487 (2007/10/02)
Epoxidic substrate analogues related to allylamine (4a-4e) and allyl alcohol (5a-5f) were synthesized and tested as models of cysteine-protease inhibitors.They proved to be irreversible inhibitors of papain and cathepsin B with pseudo-first-order inactiva
Carboxyl-Modified Amino Acids and Peptides as Protease Inhibitors
Thompson, Stewart A.,Andrews, Peter R.,Hanzlik, Robert P.
, p. 104 - 111 (2007/10/02)
Several types of carbonyl-modified amino acids and peptides were prepared in forms having N-terminal modifications (carrier fragments) suitable for one of several representative protease enzymes, and their inhibitory action toward those enzymes were evalu
