877874-85-6 Usage
Uses
Used in Pharmaceutical Industry:
4-Pyrimidinamine, 2-(methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]is used as a drug candidate for the treatment of various diseases, including cancer. It is an orally active drug that stabilizes the inactive state of PDGFRβ/B-RAF and inhibits tumor angiogenesis, which is essential for tumor growth and metastasis.
Used in Chemical Research:
4-Pyrimidinamine, 2-(methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]is also used as a research compound in chemical laboratories. Its unique structure and reactivity make it a valuable tool for studying various chemical reactions and mechanisms, as well as for the development of new synthetic methods and strategies.
Used in Material Science:
4-Pyrimidinamine,
2-(methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-
3-yl]phenoxy]may also find applications in material science, particularly in the development of new materials with unique properties. Its ability to form stable complexes and interact with other molecules could be harnessed to create novel materials with potential applications in various industries, such as electronics, energy, and environmental protection.
Check Digit Verification of cas no
The CAS Registry Mumber 877874-85-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,7,8,7 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 877874-85:
(8*8)+(7*7)+(6*7)+(5*8)+(4*7)+(3*4)+(2*8)+(1*5)=256
256 % 10 = 6
So 877874-85-6 is a valid CAS Registry Number.
877874-85-6Relevant academic research and scientific papers
THERAPEUTIC METHODS AND COMPOSITIONS INVOLVING ALLOSTERIC KINASE INHIBITION
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, (2011/09/14)
The present invention is directed to methods and compositions for suppressing lymphangiogenesis, angiogenesis and/or tumor growth. The methods comprise contacting the tumor with a compound that (i) stabilizes a protein kinase in the inactive state and (ii
HETEROCYCLIC COMPOUNDS AND METHODS OF USE
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Page/Page column 96-97, (2010/10/20)
Heterocyclic compounds derived from benzotriazine, triazines, triazoles and oxadiazoles are disclosed. The methods of synthesis and of use of such heterocyclic compounds are also provided.
