87797-23-7

Upstream product

• 5101-01-9 4-(3,4,5-trimethoxy-phenyl)-butyric acid 
• 174506-29-7 5-(but-3-en-1-yl)-1,2,3-trimethoxybenzene 
• 79117-98-9 methyl 4-(3,4,5-trimethoxyphenyl)butanoate 
• 90-50-6 3,4,5-trimethoxycinnamic acid 
• 2675-79-8 1-bromo-3,4,5-trimethoxybenzene 
• 95198-62-2 4-(3,4,5-Trimethoxy-phenyl)-but-3-yn-1-ol 

Downstream Products

• 102222-57-1 4-(3,4,5-trimethoxyphenyl)butyl methanesulphonate 
• 87797-14-6 4-(3,4,5-trimethoxyphenyl)butyl bromide 
• 87797-20-4 5-[4-(4,4-Dimethoxy-cyclohexa-2,5-dienylidene)-butyl]-1,2,3-trimethoxy-benzene 
• 87797-22-6 1-(4-methoxyphenyl)-6,7,8-trimethoxytetralin 
• 87797-17-9 4-(3,4,5-trimethoxyphenyl)butyl triphenylphosphonium bromide 

Relevant academic research and scientific papers

GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE

The present invention discloses a glycoside compound represented by Formula III, and a preparation method, a composition, use and an intermediate thereof. The glycoside compound provided in the present invention has simple preparation method, can significantly increase the expression of VEGF-A mRNA, and is effective in promoting the angiogenesis. This provides a reliable guarantee for the development of drugs with pro-angiogenic activity for treating cerebral infarction cerebral stroke, myocardial infarction, and ischemic microcirculatory disturbance of lower limbs.

Intramolecular anodic olefin coupling reactions and the use of electron-rich aryl rings

The utility of intramolecular anodic olefin coupling reactions involving electron-rich aromatic rings for constructing fused, bicyclic ring skeletons has been examined. Reactions involving alkoxy-substituted phenyl rings were found to benefit strongly from a 3-methoxy substituent on the phenyl ring. Although overoxidation of the bicyclic product was observed in these reactions, this problem could be minimized with the use of controlled potential electrolysis conditions when a monomethoxy phenyl ring was used and avoided entirely with the use of a vinyl sulfide moiety as the initiator when a more electron-rich phenyl ring was used. Reactions involving 4-alkoxy-substituted phenyl rings as substrates did not lead to good yields of fused products. Furan rings were found to be excellent coupling partners for the reactions and afforded products having fused, bicyclic furan ring skeletons. Cyclizations involving furans were shown to be compatible with the formation of both six- and seven-membered rings, the generation of a quaternary carbon, and the use of a variety of electron-rich olefins as the other coupling partner. It appears that the furan can serve as either the initiating group or the terminating group for the cyclizations. Finally, the reactions were shown to be compatible with the use of a pyrrole ring as one of the participants.

The Enantiospecific Nicholas Reaction

The enantiospecific Nicholas reaction, i.e. cobalt-promoted Friedel-Crafts reaction leading from chiral reactant to chiral product, was demonstrated for the first time. - Key Words: Nicholas reaction; enantiospecific; cobalt-stabilized carborations; 1-ethynyltetralin

An approach to the biomimetic synthesis of aryltetralin lignans

The BF3 catalysed cyclisation of 3-arylpropyl substituted quinone-methide ketals affords a mild, biomimetic route to aryltetralins. 1H- and 13C-NMR spectra of the products are reported.