877994-35-9Relevant academic research and scientific papers
Diastereo- and Enantioselective Synthesis of β-Aminoboronate Esters by Copper(I)-Catalyzed 1,2-Addition of 1,1-Bis[(pinacolato)boryl]alkanes to Imines
Kim, Jeongho,Ko, Kwangwook,Cho, Seung Hwan
supporting information, p. 11584 - 11588 (2017/09/12)
Reported herein is an efficient copper(I)-catalytic system for the diastereo- and enantioselective 1,2-addition of 1,1-bis[(pinacolato)boryl]alkanes to protected imines to afford synthetically valuable enantioenriched β-aminoboron compounds bearing contiguous stereogenic centers. The reaction exhibits a broad scope with respect to protected imines and 1,1-bis[(pinacolato)boryl]alkanes, thus providing β-aminoboronate esters with excellent diastereo- and enantioselectivity. The synthetic utility of the obtained β-aminoboronate ester was also demonstrated.
Bioinspired polyene cyclization promoted by intermolecular chiral acetal-SnCl4 or chiral N-acetal-TiCl4: Investigation of the mechanism and identification of the key intermediates
Zhao, Yu-Jun,Loh, Teck-Peng
supporting information; experimental part, p. 10024 - 10029 (2009/02/04)
New strategies using chiral acetal or chiral mixed-acetal in the presence of Lewis acids (SnCl4 or TiCl4) to promote polyene cyclization reaction are described. Acetal-promoted and mixed-acetal-promoted polyene cyclization products a
