878006-96-3Relevant academic research and scientific papers
The catalytic asymmetric Claisen rearrangement (CAC) in natural product synthesis: Synthetic studies toward curvicollides A-C
K?rner, Marleen,Hiersemann, Martin
, p. 121 - 123 (2006)
A catalytic asymmetric Claisen rearrangement has been utilized as key C-C connecting transformation for the synthesis of a building block in the projected total synthesis of the fungicidal polyketides curvicollide A-C. Georg Thieme Verlag Stuttgart.
Advances and Setbacks in the Total Synthesis of the Fungal Metabolite Curvicollide C: Synthesis and Elaboration of Non-Aldol Stereotriads from Gosteli-Type Allyl Vinyl Ethers
K?rner, Marleen,Hiersemann, Martin
, p. 2466 - 2482 (2016/07/28)
Advances and setbacks are reported in regard to the asymmetric total synthesis of the fungal metabolite curvicollide C relying on a synthetic strategy that exploits non-aldol stereotriads as chiral building blocks. A catalytic asymmetric Gosteli-Claisen rearrangement, a two-step aldehyde-to-alkyne-homologation, and a Julia-Kocienski olefination served as key C/C-connecting transformations.
