87807-95-2Relevant academic research and scientific papers
ACETOPHENONE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS
-
Page 31-32, (2010/11/30)
The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutama
Hydroxyacetophenone-derived antagonists of the peptidoleukotrienes
Brown,Bersntein,Cronk,Dossett,Hebbel,Maduskuie Jr.,Shapiro,Vacek,Yee,Willard,Krell,Snyder
, p. 807 - 826 (2007/10/02)
Considerations of the possible similarities between leukotriene D4 and its prototypical antagonist, FPL 55712, led to the development of a new series of leukotriene antagonists incorporating a hydroxyacetophenone group (e.g., the toluic acids 1
DERIVATIVES OF 4-ACETYL-3-HYDROXY-2-ALKYL-PHENOXYCARBOXYLIC ACIDS
-
, (2008/06/13)
The invention relates to compounds of the formula STR1 wherein R is hydrogen or lower alkyl, Y is alkylene; Z is alkylene, STR2 the asterisk herein denotes bonding to the substituted acetophenone; R 2 is hydrogen or lower alkoxy; and n is an integer of 1
Pharmaceutically active phenylcarboxylic acid derivatives
-
, (2008/06/13)
Compounds which antagonize the slow-reacting substance of anaphylaxis or components thereof, e.g., leukotrienes, in warm blooded animals as well as intermediates and methods for their preparation, pharmaceutical compositions and methods for their administration. The compounds are diphenyl carboxylic acids with particular linking groups between the individual phenyl rings and the carboxylic acid moiety. Particular utilities are to relieve asthma and inflammation in man.
