87815-76-7

Basic information

• Product Name: 4-bromo-N-cyclohexyl-2-nitroaniline
• Synonyms: 4-bromo-N-cyclohexyl-2-nitroaniline
• CAS NO: 87815-76-7
• Molecular Weight: 299.167
• Mol File: 87815-76-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-bromo-N-cyclohexyl-2-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-N-cyclohexyl-2-nitroaniline(87815-76-7)
• EPA Substance Registry System: 4-bromo-N-cyclohexyl-2-nitroaniline(87815-76-7)

Safety Data

• Hazardous Substances Data: 87815-76-7(Hazardous Substances Data)

Upstream product

• 33696-00-3 4-bromo-1-methoxy-2-nitrobenzene 
• 108-91-8 cyclohexylamine 
• 106-37-6 1.4-dibromobenzene 
• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 

Relevant articles and documents

Synthesis and: In vitro evaluation of naphthalimide-benzimidazole conjugates as potential antitumor agents

A series of novel naphthalimide-benzimidazoles was designed and synthesized for the first time and studied for their effect on antiproliferative activity. Some of these compounds possessed good antitumor activity towards the tested cancer cell lines. Noticeably, (diethylamino)ethyl 15 and (dimethylamino)ethyl 23 derivatives displayed superior antiproliferative activity towards human cancer cell lines with MG-MID GI50 values of 1.43 and 1.83 μM, respectively. Preliminary investigation revealed that compounds 15 and 23 might bind with ct-DNA through the intercalation mode which is responsible for potent bioactivity. Moreover, transportation behaviour indicated that these molecules could efficiently bind to and be carried by bovine albumin, and the hydrogen bonding and hydrophobic interactions played important roles in interaction with serum albumin.

Compound Shape Effects in Minor Groove Binding Affinity and Specificity for Mixed Sequence DNA

AT specific heterocyclic cations that bind in the DNA duplex minor groove have had major successes as cell and nuclear stains and as therapeutic agents which can effectively enter human cells. Expanding the DNA sequence recognition capability of the minor