878158-08-8

Basic information

• Product Name: Carbamic acid, [2-(3-ethenylphenyl)ethyl]-, 1,1-dimethylethyl ester
• CAS NO: 878158-08-8
• Molecular Formula: C15H21NO2
• Molecular Weight: 247.337
• Mol File: 878158-08-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-(3-ethenylphenyl)ethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-(3-ethenylphenyl)ethyl]-, 1,1-dimethylethyl ester(878158-08-8)
• EPA Substance Registry System: Carbamic acid, [2-(3-ethenylphenyl)ethyl]-, 1,1-dimethylethyl ester(878158-08-8)

Safety Data

• Hazardous Substances Data: 878158-08-8(Hazardous Substances Data)

Upstream product

• 259538-59-5 2-(3'-vinyl-phenyl)-ethylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 7486-35-3 tri-n-butyl(vinyl)tin 
• 153732-25-3 [2-(3-bromophenyl)ethyl]carbamic acid tert-butyl ester 
• 3132-99-8 m-bromobenzoic aldehyde 
• 14473-91-7 3-bromocinnamic acid 
• 3650-77-9 methyl 3-(3'-bromophenyl)-acrylate 
• 151583-29-8 methyl 3-(3'-bromophenyl)-propionate 
• 42287-90-1 3-(3-bromophenyl)propanoic acid 

Downstream Products

• 878158-09-9 trans-methyl 3-(3'-{2''-[3'''-(2''''-tert-butoxycarbonylaminoethyl)phenyl]vinyl}phenyl)-propionate 
• 878158-10-2 (E)-1-(3-(2-aminoethyl)phenyl)-2-(O-methyl hydrocinnam-3’-yl)-ethene 
• 878158-11-3 methyl trans-3-{3-[2-[3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]phenyl]vinyl]phenyl}propionate 
• 878158-12-4 trans-3-{3-[2-[3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]phenyl]vinyl]phenyl}propionic acid 

Relevant articles and documents

Phototriggerable peptidomimetics for the inhibition of Mycobacterium tuberculosis ribonucleotide reductase by targeting protein-protein binding

Incorporation of an artificial amino acid 2 with a stilbene chromophore into peptidomimetics with three to nine amino acids yields phototriggerable candidates for inhibition of the binding between the R1 and R2 subunits of the M. tuberculosis ribonucleotide reductase (RNR). Interstrand hydrogen bond probability was used as a guideline for predicting conformational preferences of the photoisomers. Binding of these inhibitors has been rationalized by docking studies with the R1 unit. Significant differences in binding of the photoisomers were observed. For the shorter peptidomimetics, stronger binding of the Z isomer might indicate hydrophobic interactions between the stilbene chromophore and the binding site. This journal is

Chemistry and folding of photomodulable peptides - Stilbene and thioaurone-type candidates for conformational switches

Optimized synthetic strategies for the preparation of photoswitchable molecular scaffolds based on stilbene or on thioaurone chromophores and their conformationally directing properties, as studied by computations and by NMR spectroscopy, are addressed. For the stilbene peptidomimetics 1, 2 and 3, the length of connecting linkers between the chromophore and the peptide strands was varied, resulting in photochromic dipeptidomimetics with various flexibility. Building blocks of higher rigidity, based on para-substituted thioaurone (4 and 6) and meta-substituted thioaurone chromophores (5 and 7) are shown to have a stronger conformationally directing effect. Design, synthesis, theoretical and experimental conformational analyses are presented.