878197-72-9Relevant academic research and scientific papers
CXCR4 INHIBITORS AND USES THEREOF
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, (2018/04/11)
The present invention provides compounds, compositions thereof, and methods of using the same.
CXCR4 INHIBITORS AND USES THEREOF
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Paragraph 00360; 00361, (2018/04/11)
The present invention provides compounds, compositions thereof, and methods of using the same.
Kilogram-scale synthesis of the CXCR4 antagonist GSK812397
Boggs, Sharon,Elitzin, Vassil I.,Gudmundsson, Kristjan,Martin, Michael T.,Sharp, Matthew J.
scheme or table, p. 781 - 785 (2010/04/22)
An improved, scalable synthesis of the CXCR4 antagonist GSK812397 is described. This new route was recently scaled up in 50 L fixed equipment to afford 1.2 kg of drug substance in five steps with an overall yield of 20% and >99% chemical and enantiomeric
CHEMICAL COMPOUNDS
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Page/Page column 49-50, (2010/11/28)
The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a
CHEMICAL COMPOUNDS
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Page/Page column 37, (2008/06/13)
The present invention provides compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind to chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 of a
CHEMICAL COMPOUNDS
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Page/Page column 71, (2010/11/08)
The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a recep
CHEMICAL COMPOUNDS
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Page/Page column 41, (2008/06/13)
There is provided novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as C
CHEMCIAL COMPOUNDS
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Page/Page column 61, (2010/10/20)
The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.
