878277-38-4

Basic information

• Product Name: (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone
• Synonyms: (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone
• CAS NO: 878277-38-4
• Molecular Weight: 410.51
• Mol File: 878277-38-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone(878277-38-4)
• EPA Substance Registry System: (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone(878277-38-4)

Safety Data

• Hazardous Substances Data: 878277-38-4(Hazardous Substances Data)

Upstream product

• 888481-17-2 (3S)-3-((tert-butyldimethylsilanyl)oxy)-3,7-dimethyloct-6-en-1-ol 
• 1326774-94-0 (6S)-6,8-bis-(tert-butyldimethylsilanyloxy)-2,6-dimethyl-oct-2-ene 
• 50727-94-1 [3-methyl-3-(4-methylpent-3-enyl)oxiran-2-yl]methanol 
• 123748-58-3 (3S)-3,7-dimethyl-oct-6-ene-1,3-diol 
• 1528767-73-8 (E)-1-{(3″S)-[3″-(tert-butyldimethylsilanyloxy)-3″,7″-dimethyloct-6″-enyl]-2′,4′-dihydroxyphenyl}-3-(4-hydroxyphenyl)propenone 
• 1528767-72-7 1-{(3″S)-[3″-(tert-butyldimethylsilanyloxy)-3″,7″-dimethyloct-6-enyl]-2′,4′-dihydroxyphenyl}ethanone 
• 1528767-71-6 (1S)[1-(2′-bromoethyl)-1,5-dimethylhex-4-enyloxy]tert-butyldimethylsilane 

Relevant articles and documents

Total synthesis and assignment of the absolute stereochemistry of xanthoangelol J: Development of a highly efficient method for Claisen-Schmidt condensation Dedicated to Late (Dr.) Jadab C. Sarma on his 55th birthday on first May 2013

The first total synthesis of cancer chemopreventive terpenyl hydroxychalcone xanthoangelol J isolated from Angelica keiskei was accomplished with asymmetric epoxidation, aromatic C-alkylation and Claisen-Schmidt condensation via enol mode as key steps. The crucial Claisen-Schmidt condensation has been accomplished by a novel green method using KHSO 4-SiO2 as a recyclable catalyst under microwave activation. The absolute configuration of the molecule was also determined.