87849-03-4

Usage

Usage

Building block for the synthesis of various drugs and medications in the pharmaceutical industry; potential medicinal properties in the treatment of pain and inflammation

Applications

Organic chemistry for the preparation of other compounds with similar structural motifs.

Upstream product

• 50-00-0 formaldehyd 
• 25150-61-2 pyrrolidine hydrochloride 
• 122-00-9 para-methylacetophenone 
• 123-75-1 pyrrolidine 

Downstream Products

• 145880-01-9 3-((E)-3-Pyrrolidin-1-yl-1-p-tolyl-propenyl)-pyridine 
• 145880-03-1 3-((Z)-3-Pyrrolidin-1-yl-1-p-tolyl-propenyl)-pyridine 
• 70708-28-0 1-[2]pyridyl-3-pyrrolidino-1-p-tolyl-propan-1-ol 
• 87848-99-5 acrivastine 
• 87849-04-5 2-[1-hydroxy-3-pyrrolidino-1-(4-tolyl)-propyl]pyridine-6-aldehyde 

Relevant academic research and scientific papers

Evaluation of Cytotoxic Properties of N,N'-bis[(1-aryl-3-heteroaryl)propylidene]-hydrazine dihydrochlorides

N,N'-bis[(1-aryl-3-heteroaryl)propylidene]hydrazine dihydrochlorides, P1, P4 – P8, and R1 – R7, were assayed against human oral squamous cell carcinoma (HSC-2, HSC-3, HSC-4), human promyelocytic leukemia cell line (HL-60), and human normal oral cells (HGF

ARALKYL DIAMINE DERIVATIVES AND USES THEREOF AS ANTIDEPRESSANT

Aralkyl diamine derivative of the following formula, pharmaceutically acceptable salts or uses thereof as antidepressants. The derivatives have triplex inhibiting activities of the reuptake of 5-HT, dopamine and noradrenalin, which can be administered to the patients in need of such treatment in the form of compositions orally or injectedly et al.

A PROCESS FOR PREPARATION OF E-ISOMER OF 1-(4-METHYLPHENYL)- 1-(2-PYRID YL)-3-PYRROLIDINO PROP-1-ENE AND ACID ADDITION SALTS THEREOF

A process for preparation of E-isomer of 1-(4-methylphenyl)-1-(2-pyridyl)-3- pyrrolidinoprop-1-ene of Formula-I, and acid addition salts thereof, said process comprising; dehydrating 1-(4-methylphenyl)-l -(2-pyridyl)-3-pyrrolidinopropan-1-ol of Formula III followed by adding a base solution to obtain a mixture of E and Z isomers of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene, and washing said mixture of E and Z isomers of 1-(4-methylphenyl)-1-(2-pyridyl)-3- pyrrolidinoprop-1-ene with water to dissolve Z isomer and to obtain E-isomer of 1- (4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene of Formula I, which is substantially free from Z isomer.