87850-41-7Relevant academic research and scientific papers
Arylnaphthalene lignans as novel series of hypolipidemic agents raising high-density lipoprotein level
Iwasaki,Kondo,Nishitani,Kuroda,Hirakoso,Ohtani,Takashima
, p. 1701 - 1705 (2007/10/03)
A series of arylnaphthalene lignans were synthesized and tested for hypolipidemic activity. The most potent compound (4b) (TA-7552) not only reduced serum cholesterol, but also increased high-density lipoproteins cholesterol in rats. The effective dose of
Hydroxyacetals, phtalans, and isobenzofurans therefrom
Keay, Brian A.,Plaumann, Heinz P.,Rajapaksa, Dayananda,Rodrigo, Russell
, p. 1987 - 1995 (2007/10/02)
A general method for the generation of isobenzofuran intermediates is described.Lithiated aromatic acetals are converted to hydroxyacetals (A) which may be cyclized to isobenzofurans by mild acid treatment through the 1-hydroxyphtalans (B).The isobenzofur
