87853-48-3Relevant academic research and scientific papers
The chemistry of indoles. CIII. Simple syntheses of serotonin, N-methylserotonin, bufotenine, 5-methoxy-N-methyltryptamine, bufobutanoic acid, N-(indol-3-yl)methyl-5-methoxy-N-methyltryptamine, and lespedamine based on 1-hydroxyindole chemistry
Somei,Yamada,Kurauchi,Nagahama,Hasegawa,Yamada,Teranishi,Sato,Kaneko
, p. 87 - 96 (2007/10/03)
Application of regioselective nucleophilic substitution reactions of 1-hydroxytryptamines to novel and simple syntheses of serotonin (1a), N-methylserotonin (1b), bufotenine (1c), 5-methoxy-N-methyltryptamine (2a), bufobutanoic acid (3a), N-(indol-3-yl)methyl-5-methoxy-N-methyltryptamine (4), and lespedamine (5) are described. Effective syntheses of 5-benzyloxytryptamine and 1-methoxy-2-oxindoles are also reported.
A SHORT STEP SYNTHESIS OF LESPEDAMINE
Somei, Masanori,Sato, Haruhiko,Kaneko, Chikara
, p. 1797 - 1799 (2007/10/02)
A convenient synthetic method for 1-hydroxy-, 1-methoxy-, and 1-acetoxy-2-oxindole was disclosed starting from methyl 2-nitrophenylacetate.A five-step synthesis of lespedamine was achieved utilizing this method.
